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Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement.
Moss, Neil; Xiong, Zhaoming; Burke, Mike; Cogan, Derek; Gao, Donghong A; Haverty, Kathleen; Heim-Riether, Alexander; Hickey, Eugene R; Nagaraja, Raj; Netherton, Matthew; O'Shea, Kathy; Ramsden, Philip; Schwartz, Racheline; Shih, Daw-Tsun; Ward, Yancey; Young, Erick; Zhang, Qing.
Affiliation
  • Moss N; Department of Medicinal Chemistry, Immunology and Inflammation, Boehringer Ingelheim Pharmaceutical, Inc., 900 Ridgebury Road, Ridgefield, CT 06877, USA. Neil.Moss@comcast.com
Bioorg Med Chem Lett ; 22(23): 7189-93, 2012 Dec 01.
Article in En | MEDLINE | ID: mdl-23084902

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protease Inhibitors / Thiophenes / Triazoles / Cathepsins / Amides Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protease Inhibitors / Thiophenes / Triazoles / Cathepsins / Amides Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido