Nociceptive thresholds of the response to lipopolysaccharide injection into the limbic structures of the brain in rats.
Bull Exp Biol Med
; 153(5): 730-3, 2012 Sep.
Article
in En
| MEDLINE
| ID: mdl-23113271
ABSTRACT
Microinjections of LPS into the limbic structures of rat brain (dorsal hippocampus and caudal compartment of the cingulate fascicle) caused opposite effects on the nociceptive thresholds injection into the dorsal hippocampus enhanced perception and reduced the emotional affective perception of pain, while injection into the cingulate fascicle reduced the perceptual and enhanced the emotional components of the nociceptive reaction. These results indicated specific involvement of these limbic structures in nociception modulation during induction of the immune response in CNS.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Lipopolysaccharides
/
Pain Threshold
/
Emotions
/
Pain Perception
/
Nociceptive Pain
/
Limbic System
Limits:
Animals
Language:
En
Journal:
Bull Exp Biol Med
Year:
2012
Document type:
Article
Affiliation country:
Rusia
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA