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Plasmid content of a clinically relevant Klebsiella pneumoniae clone from the Czech Republic producing CTX-M-15 and QnrB1.
Dolejska, Monika; Villa, Laura; Dobiasova, Hana; Fortini, Daniela; Feudi, Claudia; Carattoli, Alessandra.
Affiliation
  • Dolejska M; Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.
Antimicrob Agents Chemother ; 57(2): 1073-6, 2013 Feb.
Article in En | MEDLINE | ID: mdl-23229477
ABSTRACT
The entire plasmid content of a multidrug-resistant, CTX-M-15-producing Klebsiella pneumoniae ST416 clone was investigated. Two FII(K) plasmids, pKDO1 (127 kb) and pKPN-CZ (207 kb), were identified and found to carry a formidable set of genes conferring resistance to toxic compounds, metals, and antimicrobial drugs and exhibiting novel features putatively associated with adaptation and fitness of the bacterium in the human host.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmids / Bacterial Proteins / Beta-Lactamases / Klebsiella pneumoniae Country/Region as subject: Europa Language: En Journal: Antimicrob Agents Chemother Year: 2013 Document type: Article Affiliation country: República Checa

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmids / Bacterial Proteins / Beta-Lactamases / Klebsiella pneumoniae Country/Region as subject: Europa Language: En Journal: Antimicrob Agents Chemother Year: 2013 Document type: Article Affiliation country: República Checa