Soft substrates normalize nuclear morphology and prevent nuclear rupture in fibroblasts from a laminopathy patient with compound heterozygous LMNA mutations.

Tamiello, Chiara; Kamps, Miriam A F; van den Wijngaard, Arthur; Verstraeten, Valerie L R M; Baaijens, Frank P T; Broers, Jos L V; Bouten, Carlijn C V

Tamiello, Chiara; Kamps, Miriam A F; van den Wijngaard, Arthur; Verstraeten, Valerie L R M; Baaijens, Frank P T; Broers, Jos L V; Bouten, Carlijn C V.

Affiliation

Tamiello C; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands. c.tamiello@tue.nl

Nucleus ; 4(1): 61-73, 2013.

Article in En | MEDLINE | ID: mdl-23324461

Subject(s)
Key words

lamina; laminopathies; nuclear rupture; nuclear shape alteration; substrate stiffness

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Nucleus / Lamin Type A Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nucleus Year: 2013 Document type: Article Affiliation country: Países Bajos Country of publication: Estados Unidos

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