Familial adenomatous polyposis: not all masses are desmoids.
Fam Cancer
; 12(3): 525-8, 2013 Sep.
Article
in En
| MEDLINE
| ID: mdl-23397065
ABSTRACT
Familial adenomatous polyposis (FAP) is a multi-system disease characterised by the development of hundreds to thousands of colorectal adenomas which inevitably progress to carcinoma without treatment. It is commonly associated with extra colonic lesions including osteomas, epidermoid cysts and desmoid tumours. Desmoid tumours are troublesome due to their size and bulk and are a significant cause of morbidity and mortality in FAP. This series highlights three cases in which patients with FAP developed masses thought initially to be manifestations of the condition. Further investigation in fact demonstrated neurofibromatosis type 1 in all three patients. All masses in FAP patients cannot be assumed to be disease related (desmoid, osteoma, epidermoid cyst or carcinoma).
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Neurofibromatoses
/
Fibromatosis, Aggressive
/
Adenomatous Polyposis Coli
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Fam Cancer
Journal subject:
NEOPLASIAS
Year:
2013
Document type:
Article