Second harmonic generation in 3-d uniform arrangement of type I collagen on nonlinear optics microscopy.
Scanning
; 35(1): 12-6, 2013.
Article
in En
| MEDLINE
| ID: mdl-23417663
ABSTRACT
Second harmonic microscopic imaging and spectroscopy technology has become a powerful tool for biomedical studies, especially in fibrosis-related diseases research. And type I collagen is the major risk factors for fibrotic diseases. In this study, model for three-dimensional (3-D) uniform arrangement type I collagen is set up for researching the second harmonic generation (SHG) on nonlinear optics microscopy. Based on this model, we discuss the influence of different length and size collagen in 3-D arrangement type I collagen. Results can guide us to neatly judge the size, length, and molecules density effect on SHG. For practical application, this theoretical approach can lead us to analyze different severity of collagen diseases.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spectrum Analysis
/
Collagen Type I
/
Microscopy
Type of study:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Language:
En
Journal:
Scanning
Year:
2013
Document type:
Article
Affiliation country:
China