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Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth.
Trisciuoglio, Daniela; De Luca, Teresa; Desideri, Marianna; Passeri, Daniela; Gabellini, Chiara; Scarpino, Stefania; Liang, Chengyu; Orlandi, Augusto; Del Bufalo, Donatella.
Affiliation
  • Trisciuoglio D; Experimental Chemotherapy Laboratory, Regina Elena National Cancer Institute, Rome, Italy.
Neoplasia ; 15(3): 315-27, 2013 Mar.
Article in En | MEDLINE | ID: mdl-23479509
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Proto-Oncogene Proteins c-bcl-2 / Protein Interaction Domains and Motifs / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Neoplasia Journal subject: NEOPLASIAS Year: 2013 Document type: Article Affiliation country: Italia Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Proto-Oncogene Proteins c-bcl-2 / Protein Interaction Domains and Motifs / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Neoplasia Journal subject: NEOPLASIAS Year: 2013 Document type: Article Affiliation country: Italia Country of publication: Estados Unidos