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Intermittent minodronic acid treatment with sufficient bone resorption inhibition prevents reduction in bone mass and strength in ovariectomized rats with established osteopenia comparable with daily treatment.
Kimoto, Aishi; Tanaka, Makoto; Nozaki, Kazutoshi; Mori, Masamichi; Fukushima, Shinji; Mori, Hiroshi; Shiroya, Tsutomu; Nakamura, Toshitaka.
Affiliation
  • Kimoto A; Pharmacology Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Tsukuba, Ibaraki 305-8585, Japan.
Bone ; 55(1): 189-97, 2013 Jul.
Article in En | MEDLINE | ID: mdl-23486179
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone and Bones / Bone Diseases, Metabolic / Bone Resorption / Ovariectomy / Diphosphonates / Imidazoles Limits: Animals Language: En Journal: Bone Journal subject: METABOLISMO / ORTOPEDIA Year: 2013 Document type: Article Affiliation country: Japón Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone and Bones / Bone Diseases, Metabolic / Bone Resorption / Ovariectomy / Diphosphonates / Imidazoles Limits: Animals Language: En Journal: Bone Journal subject: METABOLISMO / ORTOPEDIA Year: 2013 Document type: Article Affiliation country: Japón Country of publication: Estados Unidos