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Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1).
Reipas, Kristen M; Law, Jennifer H; Couto, Nicole; Islam, Sumaiya; Li, Yvonne; Li, Huifang; Cherkasov, Artem; Jung, Karen; Cheema, Amarpal S; Jones, Steven J M; Hassell, John A; Dunn, Sandra E.
Affiliation
  • Reipas KM; Laboratory for Oncogenomic Research, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Oncotarget ; 4(2): 329-45, 2013 Feb.
Article in En | MEDLINE | ID: mdl-23593654
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Proto-Oncogene Proteins / Ribosomal Protein S6 Kinases, 90-kDa / Luteolin / Y-Box-Binding Protein 1 / Receptors, Notch / Triple Negative Breast Neoplasms Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Oncotarget Year: 2013 Document type: Article Affiliation country: Canadá
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Proto-Oncogene Proteins / Ribosomal Protein S6 Kinases, 90-kDa / Luteolin / Y-Box-Binding Protein 1 / Receptors, Notch / Triple Negative Breast Neoplasms Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Oncotarget Year: 2013 Document type: Article Affiliation country: Canadá