Orthogonally protected D-galactosamine thioglycoside building blocks via highly regioselective, double serial and double parallel inversions of ß-D-thiomannoside.
Org Biomol Chem
; 11(29): 4825-30, 2013 Aug 07.
Article
in En
| MEDLINE
| ID: mdl-23774997
ABSTRACT
An efficient route for the synthesis of orthogonally protected D-galactosamine thioglycosides via one-pot double serial and double parallel displacements of the D-mannosyl-2,4-bis-trifluoromethanesulfonates by azide and nitrite ions is described. These building blocks were utilized to synthesize the rare disaccharide moiety of the zwitterionic polysaccharide of Bacteroides fragilis and the selectively protected Tn antigen.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Thioglycosides
/
Galactosamine
/
Mannose
Language:
En
Journal:
Org Biomol Chem
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
2013
Document type:
Article
Affiliation country:
India