Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats.
Chem Biol Interact
; 205(2): 108-18, 2013 Sep 25.
Article
in En
| MEDLINE
| ID: mdl-23830814
Key words
8-OHdG; 8-hydroxydeoxyguanosine; Aldh1a1; Apoptosis; B-cell CLL/lymphoma 2; BNF; Bax; Bcl2; Bcl2-associated X protein; Bcl2-like 1; Bcl2l1; CMD; Casp; Cd4; Cd4 molecule; Cd8a; Cd8a molecule; Col1a1; Cox-2; Cu; Cx3cl1; Cxcl10; DAB; DEN; DR5; Death receptor 5 (DR5); EMIQ; Fadd; Fas (TNFRSF6)-associated via death domain; Fe; GST-P; Gpx2; Gstm1; HO-1; Hprt; Il1b; Il4; Inflammation; Liver tumor promotion; Mapk; Mmp; N-diethylnitrosamine; NAD(P)H dehydrogenase, quinone 1; Nfe2l2; Nqo1; PBS; PCNA; Ptgs2; ROS; Serpine1; TAA; TBARS; TRAIL; TUNEL; Tgfb2; Thioacetamide (TAA); Tnf; Tnfrsf10b; Tnfsf10; Txn1; a-LA; aldehyde dehydrogenase family 1 member A1; caspase; chemokine (C-X-C motif) ligand 10; chemokine (C-X3-C motif) ligand 1; choline-methionine-deficient diet; collagen, type I, alpha 1; copper; cyclooxygenase 2; death receptor 5; diaminobenzidine; enzymatically modified isoquercitrin; glutathione S-transferase mu 1; glutathione S-transferase placental form; glutathione peroxidase 2; heme oxygenase-1; hypoxanthine guanine phosphoribosyl transferase; interleukin 1 beta; interleukin 4; iron; matrix metalloproteinase; mitogen activated protein kinase; nuclear factor, erythroid derived 2, like 2; phosphate buffered solution; proliferating cell nuclear antigen; prostaglandin-endoperoxide synthase 2; reactive oxygen species; serine (or cysteine) peptidase inhibitor, clade E, member 1; terminal deoxynucleotidyl transferase-mediated nick end labeling; thioacetamide; thiobarbituric acid-reactive substances; thioredoxin 1; transforming growth factor, beta 2; tumor necrosis factor; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor-related apoptosis-inducing ligand; α-Lipoic acid (a-LA); α-lipoic acid; ß-naphthoflavone
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Carcinogens
/
Thioctic Acid
/
Anticarcinogenic Agents
/
Liver Neoplasms, Experimental
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Chem Biol Interact
Year:
2013
Document type:
Article
Affiliation country:
Japón
Country of publication:
Irlanda