Acute infection induces a metastatic niche: a double menace for cancer patients.
Clin Cancer Res
; 19(17): 4547-9, 2013 Sep 01.
Article
in En
| MEDLINE
| ID: mdl-23922303
ABSTRACT
Tumor-derived factors can induce a premetastatic niche, yet little is known about how metastatic microenvironments are influenced by external insults, such as acute infections commonly seen in patients with cancer. New findings reveal increased metastasis to the lung after acute bacterial infection via the CXCR4/ubiquitin axis, suggesting new targets for antimetastasis therapeutics.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Receptors, CXCR4
/
Ubiquitin
/
Acute Lung Injury
/
Lung Neoplasms
Limits:
Animals
/
Humans
Language:
En
Journal:
Clin Cancer Res
Journal subject:
NEOPLASIAS
Year:
2013
Document type:
Article
Affiliation country:
Estados Unidos