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Acute infection induces a metastatic niche: a double menace for cancer patients.
Smith, Heath A; Kang, Yibin.
Affiliation
  • Smith HA; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
Clin Cancer Res ; 19(17): 4547-9, 2013 Sep 01.
Article in En | MEDLINE | ID: mdl-23922303
ABSTRACT
Tumor-derived factors can induce a premetastatic niche, yet little is known about how metastatic microenvironments are influenced by external insults, such as acute infections commonly seen in patients with cancer. New findings reveal increased metastasis to the lung after acute bacterial infection via the CXCR4/ubiquitin axis, suggesting new targets for antimetastasis therapeutics.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, CXCR4 / Ubiquitin / Acute Lung Injury / Lung Neoplasms Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2013 Document type: Article Affiliation country: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, CXCR4 / Ubiquitin / Acute Lung Injury / Lung Neoplasms Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2013 Document type: Article Affiliation country: Estados Unidos