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Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML.
Chaturvedi, Anuhar; Araujo Cruz, Michelle Maria; Jyotsana, Nidhi; Sharma, Amit; Yun, Haiyang; Görlich, Kerstin; Wichmann, Martin; Schwarzer, Adrian; Preller, Matthias; Thol, Felicitas; Meyer, Johann; Haemmerle, Reinhard; Struys, Eduard A; Jansen, Erwin E; Modlich, Ute; Li, Zhixiong; Sly, Laura M; Geffers, Robert; Lindner, Robert; Manstein, Dietmar J; Lehmann, Ulrich; Krauter, Jürgen; Ganser, Arnold; Heuser, Michael.
Affiliation
  • Chaturvedi A; Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation.
Blood ; 122(16): 2877-87, 2013 Oct 17.
Article in En | MEDLINE | ID: mdl-23954893
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Gene Expression Regulation, Leukemic / Isocitrate Dehydrogenase / Mutation Limits: Adolescent / Adult / Animals / Female / Humans / Middle aged Language: En Journal: Blood Year: 2013 Document type: Article Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Gene Expression Regulation, Leukemic / Isocitrate Dehydrogenase / Mutation Limits: Adolescent / Adult / Animals / Female / Humans / Middle aged Language: En Journal: Blood Year: 2013 Document type: Article Country of publication: Estados Unidos