RG7212 anti-TWEAK mAb inhibits tumor growth through inhibition of tumor cell proliferation and survival signaling and by enhancing the host antitumor immune response.

Yin, Xuefeng; Luistro, Leopoldo; Zhong, Hua; Smith, Melissa; Nevins, Tom; Schostack, Kathleen; Hilton, Holly; Lin, Tai-An; Truitt, Theresa; Biondi, Denise; Wang, Xiaoqian; Packman, Kathryn; Rosinski, Jim; Berkofsky-Fessler, Windy; Tang, Jian-Ping; Pant, Saumya; Geho, David; Vega-Harring, Suzana; Demario, Mark; Levitsky, Hy; Simcox, Mary

Yin, Xuefeng; Luistro, Leopoldo; Zhong, Hua; Smith, Melissa; Nevins, Tom; Schostack, Kathleen; Hilton, Holly; Lin, Tai-An; Truitt, Theresa; Biondi, Denise; Wang, Xiaoqian; Packman, Kathryn; Rosinski, Jim; Berkofsky-Fessler, Windy; Tang, Jian-Ping; Pant, Saumya; Geho, David; Vega-Harring, Suzana; Demario, Mark; Levitsky, Hy; Simcox, Mary.

Affiliation

Yin X; Authors' Affiliations: Roche Pharma Research and Early Development, Nutley, New Jersey; Roche Diagnostics GmbH, Pharma Research & Early Development, Nonnenwald, Penzberg, Germany; and Roche Pharma Research and Early Development, Roche Glycart AG, Schlieren, Switzerland.

Clin Cancer Res ; 19(20): 5686-98, 2013 Oct 15.

Article in En | MEDLINE | ID: mdl-23974006

Subject(s)

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Tumor Necrosis Factor Inhibitors / Antibodies, Monoclonal / Neoplasms / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2013 Document type: Article Affiliation country: Suiza

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google