Vitreous fluorophotometry in patients with Best's macular dystrophy.
Retina
; 10(2): 102-4, 1990.
Article
in En
| MEDLINE
| ID: mdl-2402550
ABSTRACT
Ten patients with Best's macular dystrophy were examined with vitreous fluorophotometry and results were compared with a normal population. Seventeen of the 20 affected eyes demonstrated an intact blood-retinal barrier with normal inward permeability of fluorescein dye. Despite diffuse functional impairment of the retinal pigment epithelium (RPE), determined by electro-oculography, as well as accumulation of a lipofuscin or lipofuscin-like substance within virtually all RPE cells, the blood-retinal barrier function of these cells remained intact as determined by clinical fluorophotometry. Similar findings have previously been noted in another hereditary retinal disorder (fundus flavimaculatus) in which a lipofuscin-like substance also accumulates diffusely within RPE cells.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Fluorophotometry
/
Macular Degeneration
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
Language:
En
Journal:
Retina
Year:
1990
Document type:
Article