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cGMP inhibition of type 3 phosphodiesterase is the major mechanism by which C-type natriuretic peptide activates CFTR in the shark rectal gland.
De Jonge, Hugo R; Tilly, Ben C; Hogema, Boris M; Pfau, Daniel J; Kelley, Catherine A; Kelley, Megan H; Melita, August M; Morris, Montana T; Viola, Ryan M; Forrest, John N.
Affiliation
  • De Jonge HR; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands;
Am J Physiol Cell Physiol ; 306(4): C343-53, 2014 Feb 15.
Article in En | MEDLINE | ID: mdl-24259420

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salt Gland / Chlorides / Cyclic GMP / Cystic Fibrosis Transmembrane Conductance Regulator / Natriuretic Peptide, C-Type / Fish Proteins / Dogfish / Cyclic Nucleotide Phosphodiesterases, Type 3 Limits: Animals Language: En Journal: Am J Physiol Cell Physiol Journal subject: FISIOLOGIA Year: 2014 Document type: Article Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salt Gland / Chlorides / Cyclic GMP / Cystic Fibrosis Transmembrane Conductance Regulator / Natriuretic Peptide, C-Type / Fish Proteins / Dogfish / Cyclic Nucleotide Phosphodiesterases, Type 3 Limits: Animals Language: En Journal: Am J Physiol Cell Physiol Journal subject: FISIOLOGIA Year: 2014 Document type: Article Country of publication: Estados Unidos