[Efficacy of acitretin in IgA pemphigus]. / Pemphigus à IgA: efficacité de l'acitrétine.
Ann Dermatol Venereol
; 140(12): 793-6, 2013 Dec.
Article
in Fr
| MEDLINE
| ID: mdl-24315226
ABSTRACT
BACKGROUND:
IgA pemphigus is a particular entity among autoimmune blistering intraepidermal diseases. IgA pemphigus is subdivided into two types intraepidermal neutrophilic IgA dermatosis and subcorneal pustular dermatosis. PATIENTS ANDMETHODS:
We report the case of an 82-year-old woman with intraepidermal neutrophilic IgA pemphigus associated with IgA gammopathy. The histopathological findings were unusual, with numerous large subcorneal pustules, a few pustules in the stratum spinosum, and basal IgA deposition. A favourable outcome was achieved with acitretin.DISCUSSION:
This observation is significant in that it highlights the difficulty of classification of IgA pemphigus, which is currently based on clinical and histopathological findings. There is currently no therapeutic consensus attitude but simply a set of empirical data.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Monoclonal Gammopathy of Undetermined Significance
/
Immunoglobulin A
/
Pemphigus
/
Immunoglobulin kappa-Chains
/
Acitretin
/
Keratolytic Agents
Limits:
Aged80
/
Female
/
Humans
Language:
Fr
Journal:
Ann Dermatol Venereol
Year:
2013
Document type:
Article