[Do we need congenital adrenal hyperplasia screening for premature infants?]. / Faut-il maintenir un dépistage de l'hyperplasie congénitale des surrénales pour les prématurés ?
Arch Pediatr
; 21(2): 233-6, 2014 Feb.
Article
in Fr
| MEDLINE
| ID: mdl-24361036
ABSTRACT
Congenital adrenal hyperplasia neonatal screening has been introduced in France since 1995. A recent survey has questioned its relevance in premature infants because of a high number of false positives and a low positive predictive value of 17-hydroxyprogesterone dosage. A workgroup at the French screening association (Association française de dépistage et de prévention des handicaps de l'enfant) collected all the epidemiological, clinical and biological data of premature children presenting with adrenal hyperplasia from the national cohort. Their results were compared with those of healthy premature children. All the data showed that the screening in children born before 32 weeks of gestational age is irrelevant, but that it is efficient after this term. A pilot study has been implemented in population to evaluate the opportunity to discontinue this screening in extreme preterm neonates.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Neonatal Screening
/
Adrenal Hyperplasia, Congenital
/
Infant, Extremely Low Birth Weight
/
Infant, Premature, Diseases
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limits:
Humans
/
Newborn
Country/Region as subject:
Europa
Language:
Fr
Journal:
Arch Pediatr
Year:
2014
Document type:
Article