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Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge.
De Filette, Marina; Soehle, Silke; Ulbert, Sebastian; Richner, Justin; Diamond, Michael S; Sinigaglia, Alessandro; Barzon, Luisa; Roels, Stefan; Lisziewicz, Julianna; Lorincz, Orsolya; Sanders, Niek N.
Affiliation
  • De Filette M; Laboratory of Gene Therapy, Faculty of Veterinary Sciences, Ghent University, Merelbeke, Belgium.
  • Soehle S; Institute of Virology, University of Zurich, Zurich, Switzerland.
  • Ulbert S; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.
  • Richner J; Departments of Medicine, Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America.
  • Diamond MS; Departments of Medicine, Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America.
  • Sinigaglia A; Department of Molecular Medicine, University of Padova, Padova, Italy.
  • Barzon L; Department of Molecular Medicine, University of Padova, Padova, Italy.
  • Roels S; Operational Direction Interactions and Surveillance, Veterinary and Agrochemical Research Centre (CODA/CERVA), Brussels, Belgium.
  • Lisziewicz J; Genetic Immunity, Budapest, Hungary and McLean, Virginia, United States of America.
  • Lorincz O; Genetic Immunity, Budapest, Hungary and McLean, Virginia, United States of America.
  • Sanders NN; Laboratory of Gene Therapy, Faculty of Veterinary Sciences, Ghent University, Merelbeke, Belgium.
PLoS One ; 9(2): e87837, 2014.
Article in En | MEDLINE | ID: mdl-24503579

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: West Nile Fever / West Nile virus / Viral Envelope Proteins / Vaccines, DNA / West Nile Virus Vaccines / Immunity, Cellular Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Document type: Article Affiliation country: Bélgica

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: West Nile Fever / West Nile virus / Viral Envelope Proteins / Vaccines, DNA / West Nile Virus Vaccines / Immunity, Cellular Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Document type: Article Affiliation country: Bélgica