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An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents.
Barrett, Stephanie E; Abrams, Marc T; Burke, Rob; Carr, Brian A; Crocker, Louis S; Garbaccio, Robert M; Howell, Bonnie J; Kemp, Eric A; Kowtoniuk, Robert A; Latham, Andrew H; Leander, Karen R; Leone, Anthony M; Patel, Mihir; Pechenov, Sergey; Pudvah, Nicole T; Riley, Sean; Sepp-Lorenzino, Laura; Walsh, Eileen S; Williams, J Michael; Colletti, Steven L.
Affiliation
  • Barrett SE; Department of RNA Medicinal Chemistry, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA. Electronic address: stephanie_barrett@merck.com.
  • Abrams MT; Department of RNA Biology, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Burke R; Department of Pharmacokinetics & Drug Metabolism RNA, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Carr BA; Department of Pharmacokinetics & Drug Metabolism RNA, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Crocker LS; Department of RNAi Analytical Sciences, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Garbaccio RM; Department of RNA Medicinal Chemistry, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Howell BJ; Department of RNA Biology, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Kemp EA; Department of RNAi Analytical Sciences, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Kowtoniuk RA; Department of RNA Medicinal Chemistry, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Latham AH; Department of RNAi Analytical Sciences, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Leander KR; Department of RNA Biology, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Leone AM; Department of RNAi Analytical Sciences, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Patel M; Department of RNAi Analytical Sciences, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Pechenov S; Department of RNAi Analytical Sciences, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Pudvah NT; Department of Pharmacokinetics & Drug Metabolism RNA, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Riley S; Department of RNAi Analytical Sciences, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Sepp-Lorenzino L; Department of RNA Biology, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Walsh ES; Department of RNA Biology, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Williams JM; Department of RNA Medicinal Chemistry, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Colletti SL; Department of RNA Medicinal Chemistry, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
Int J Pharm ; 466(1-2): 58-67, 2014 May 15.
Article in En | MEDLINE | ID: mdl-24607208
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ornithine / Apolipoproteins B / Peptides / Phenylalanine / Polymers / RNA, Small Interfering Limits: Animals Language: En Journal: Int J Pharm Year: 2014 Document type: Article Country of publication: Países Bajos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ornithine / Apolipoproteins B / Peptides / Phenylalanine / Polymers / RNA, Small Interfering Limits: Animals Language: En Journal: Int J Pharm Year: 2014 Document type: Article Country of publication: Países Bajos