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Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis.
Flex, Elisabetta; Jaiswal, Mamta; Pantaleoni, Francesca; Martinelli, Simone; Strullu, Marion; Fansa, Eyad K; Caye, Aurélie; De Luca, Alessandro; Lepri, Francesca; Dvorsky, Radovan; Pannone, Luca; Paolacci, Stefano; Zhang, Si-Cai; Fodale, Valentina; Bocchinfuso, Gianfranco; Rossi, Cesare; Burkitt-Wright, Emma M M; Farrotti, Andrea; Stellacci, Emilia; Cecchetti, Serena; Ferese, Rosangela; Bottero, Lisabianca; Castro, Silvana; Fenneteau, Odile; Brethon, Benoît; Sanchez, Massimo; Roberts, Amy E; Yntema, Helger G; Van Der Burgt, Ineke; Cianci, Paola; Bondeson, Marie-Louise; Cristina Digilio, Maria; Zampino, Giuseppe; Kerr, Bronwyn; Aoki, Yoko; Loh, Mignon L; Palleschi, Antonio; Di Schiavi, Elia; Carè, Alessandra; Selicorni, Angelo; Dallapiccola, Bruno; Cirstea, Ion C; Stella, Lorenzo; Zenker, Martin; Gelb, Bruce D; Cavé, Hélène; Ahmadian, Mohammad R; Tartaglia, Marco.
Affiliation
  • Flex E; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and.
  • Jaiswal M; Institut für Biochemie und Molekularbiologie II, Medizinische Fakultät der Heinrich-Heine Universitat, Düsseldorf 40225, Germany.
  • Pantaleoni F; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and.
  • Martinelli S; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and.
  • Strullu M; Genetics Department, INSERM UMR_S940, Institut Universitaire D'Hématologie (IUH), Université Paris-Diderot Sorbonne-Paris-Cité, Paris 75010, France.
  • Fansa EK; Institut für Biochemie und Molekularbiologie II, Medizinische Fakultät der Heinrich-Heine Universitat, Düsseldorf 40225, Germany.
  • Caye A; Genetics Department, INSERM UMR_S940, Institut Universitaire D'Hématologie (IUH), Université Paris-Diderot Sorbonne-Paris-Cité, Paris 75010, France.
  • De Luca A; Laboratorio Mendel, Istituto di Ricovero e Cura a Carattere Scientifico-Casa Sollievo Della Sofferenza, Rome 00198, Italy.
  • Lepri F; Ospedale Pediatrico 'Bambino Gesù', Rome 00165, Italy.
  • Dvorsky R; Institut für Biochemie und Molekularbiologie II, Medizinische Fakultät der Heinrich-Heine Universitat, Düsseldorf 40225, Germany.
  • Pannone L; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and.
  • Paolacci S; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and.
  • Zhang SC; Institut für Biochemie und Molekularbiologie II, Medizinische Fakultät der Heinrich-Heine Universitat, Düsseldorf 40225, Germany.
  • Fodale V; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and.
  • Bocchinfuso G; Dipartimento di Scienze e Tecnologie Chimiche, Università 'Tor Vergata', Rome 00133, Italy.
  • Rossi C; UO Genetica Medica, Policlinico S.Orsola-Malpighi, Bologna 40138, Italy.
  • Burkitt-Wright EM; Genetic Medicine, Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
  • Farrotti A; Dipartimento di Scienze e Tecnologie Chimiche, Università 'Tor Vergata', Rome 00133, Italy.
  • Stellacci E; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and.
  • Cecchetti S; Dipartimento di Biologia Cellulare e Neuroscienze, Istituto Superiore di Sanità, Rome 00161, Italy.
  • Ferese R; Laboratorio Mendel, Istituto di Ricovero e Cura a Carattere Scientifico-Casa Sollievo Della Sofferenza, Rome 00198, Italy.
  • Bottero L; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and.
  • Castro S; Istituto di Genetica e Biofisica 'A. Buzzati Traverso', Consiglio Nazionale Delle Ricerche, Naples 80131, Italy.
  • Fenneteau O; Biological Hematology Department and.
  • Brethon B; Pediatric Hematology Department, Robert Debré Hospital, Paris 75019, France.
  • Sanchez M; Dipartimento di Biologia Cellulare e Neuroscienze, Istituto Superiore di Sanità, Rome 00161, Italy.
  • Roberts AE; Department of Cardiology and Division of Genetics, and Department of Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
  • Yntema HG; Department of Human Genetics, Radboud University Medical Centre, and Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen 6500, The Netherlands.
  • Van Der Burgt I; Department of Human Genetics, Radboud University Medical Centre, and Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen 6500, The Netherlands.
  • Cianci P; Genetica Clinica Pediatrica, Clinica Pediatrica Università Milano Bicocca, Fondazione MBBM, A.O. S. Gerardo, Monza 20900, Italy.
  • Bondeson ML; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 75237, Sweden.
  • Cristina Digilio M; Ospedale Pediatrico 'Bambino Gesù', Rome 00165, Italy.
  • Zampino G; Istituto di Clinica Pediatrica, Università Cattolica del Sacro Cuore, Rome 00168, Italy.
  • Kerr B; Genetic Medicine, Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
  • Aoki Y; Department of Medical Genetics, Tohoku University School of Medicine, Sendai 980-8574, Japan.
  • Loh ML; Department of Pediatrics, Benioff Children's Hospital, University of California School of Medicine, and the Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94143, USA.
  • Palleschi A; Dipartimento di Scienze e Tecnologie Chimiche, Università 'Tor Vergata', Rome 00133, Italy.
  • Di Schiavi E; Istituto di Genetica e Biofisica 'A. Buzzati Traverso', Consiglio Nazionale Delle Ricerche, Naples 80131, Italy.
  • Carè A; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and.
  • Selicorni A; Genetica Clinica Pediatrica, Clinica Pediatrica Università Milano Bicocca, Fondazione MBBM, A.O. S. Gerardo, Monza 20900, Italy.
  • Dallapiccola B; Ospedale Pediatrico 'Bambino Gesù', Rome 00165, Italy.
  • Cirstea IC; Institut für Biochemie und Molekularbiologie II, Medizinische Fakultät der Heinrich-Heine Universitat, Düsseldorf 40225, Germany, Leibniz Institute for Age Research, Jena 07745, Germany.
  • Stella L; Dipartimento di Scienze e Tecnologie Chimiche, Università 'Tor Vergata', Rome 00133, Italy.
  • Zenker M; Institute of Human Genetics, University Hospital of Magdeburg, Otto-von-Guericke-University, Magdeburg 39120, Germany.
  • Gelb BD; Department of Pediatrics and Department of Genetics and Department of Genomic Sciences, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Cavé H; Genetics Department, INSERM UMR_S940, Institut Universitaire D'Hématologie (IUH), Université Paris-Diderot Sorbonne-Paris-Cité, Paris 75010, France.
  • Ahmadian MR; Institut für Biochemie und Molekularbiologie II, Medizinische Fakultät der Heinrich-Heine Universitat, Düsseldorf 40225, Germany.
  • Tartaglia M; Dipartimento di Ematologia, Oncologia e Medicina Molecolare and marco.tartaglia@iss.it.
Hum Mol Genet ; 23(16): 4315-27, 2014 Aug 15.
Article in En | MEDLINE | ID: mdl-24705357
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Ras Proteins / Carcinogenesis / Mutation Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2014 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Ras Proteins / Carcinogenesis / Mutation Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2014 Document type: Article