The influence of four different anticoagulants on dynamic light scattering of platelets.
Vox Sang
; 107(2): 196-9, 2014 Aug.
Article
in En
| MEDLINE
| ID: mdl-24712311
ABSTRACT
For testing of dynamic light scattering of platelets with ThromboLUX (TLX) in platelet-rich plasma (PRP) derived from venous whole blood (vWB), anticoagulation is needed. We compared TLX score in PRPs containing citrate, ethylene-diamine-tetraacetic-acid (EDTA), citrate-phosphate-dextrose-adenine (CPDA) or citrate-theophylline-adenosine-dipyridamole. Initial and late TLX scores were measured after 30-120 min or four to six hours, respectively. Compared with citrate, mean differences in initial TLX score were only significant for CPDA. Also, mean differences between initial and late TLX scores were only significant for CPDA. TLX failed to detect EDTA-induced platelet alterations. The clinical relevance of TLX needs further studies.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phosphates
/
Theophylline
/
Blood Platelets
/
Adenine
/
Citrates
/
Dipyridamole
/
Glucose
/
Anticoagulants
Limits:
Humans
Language:
En
Journal:
Vox Sang
Year:
2014
Document type:
Article
Affiliation country:
Alemania