The impact of implementation of the Canadian regulatory requirements on the quality of natural health products: the glucosamine case.
J Pharm Pharm Sci
; 17(1): 20-4, 2014.
Article
in En
| MEDLINE
| ID: mdl-24735759
ABSTRACT
PURPOSE:
We investigated whether the recent implementation of the regulatory requirements for the entry to the Canadian market of natural products has resulted in improved quality of the available glucosamine products.METHODS:
Eleven available products, of which 8 had been tested in 2002 (7 had contained substantially lower than the label claim of the active ingredient), and a European pharmaceutical grade tablet were assayed for their glucosamine content. The potassium and sodium contents of the products were also tested.RESULTS:
Nine of the 11 Canadian products and the European tablet had more than 91% of the label claim of the active ingredient, hence, met the criterion. Two products contained 71 and 78% label claim. The electrolyte contents were very variable but constituted only a small fraction of the daily requirements.CONCLUSION:
Most tested glucosamine products passed the Health Canada requirements. This improvement is likely due to the publicity regarding the low quality of the products in the past and also a result, at least in part, of the introduction of the new regulatory requirements. The sub-standard quality of a few tested products is still of concern.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biological Products
/
Drug and Narcotic Control
/
Glucosamine
Limits:
Humans
Language:
En
Journal:
J Pharm Pharm Sci
Journal subject:
FARMACIA
/
FARMACOLOGIA
Year:
2014
Document type:
Article