Camptothecin/analogs & derivatives; Carcinoma, Non-Small-Cell Lung/drug therapy; Lung Neoplasms/drug therapy; Lung/drug effects; Neoplasms/drug therapy; Organosilicon Compounds/administration & dosage; Topoisomerase I Inhibitors/administration & dosage; Adult; Animals; Biopsy, Large-Core Needle; Camptothecin/administration & dosage; Camptothecin/adverse effects; Camptothecin/pharmacokinetics; Camptothecin/therapeutic use; Carcinoma, Non-Small-Cell Lung/blood; Carcinoma, Non-Small-Cell Lung/metabolism; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Administration Schedule; Feasibility Studies; Female; Humans; Lung/metabolism; Lung Neoplasms/blood; Lung Neoplasms/metabolism; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasms/blood; Neoplasms/metabolism; Neoplasms/pathology; Organosilicon Compounds/adverse effects; Organosilicon Compounds/pharmacokinetics; Organosilicon Compounds/therapeutic use; Pilot Projects; Random Allocation; Survival Analysis; Tissue Distribution; Topoisomerase I Inhibitors/adverse effects; Topoisomerase I Inhibitors/pharmacokinetics; Topoisomerase I Inhibitors/therapeutic use; Xenograft Model Antitumor Assays