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Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.
Shilling, Dustin; Müller, Marioly; Takano, Hajime; Mak, Don-On Daniel; Abel, Ted; Coulter, Douglas A; Foskett, J Kevin.
Affiliation
  • Shilling D; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
  • Müller M; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
  • Takano H; Departments of Pediatrics, Neurology, and Neuroscience, Perelman School of Medicine, University of Pennsylvania and the Division of Neurology and the Pediatric Regional Epilepsy Program, the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.
  • Mak DO; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
  • Abel T; Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, and.
  • Coulter DA; Departments of Pediatrics, Neurology, and Neuroscience, Perelman School of Medicine, University of Pennsylvania and the Division of Neurology and the Pediatric Regional Epilepsy Program, the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.
  • Foskett JK; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 foskett@mail.med.upenn.edu.
J Neurosci ; 34(20): 6910-23, 2014 May 14.
Article in En | MEDLINE | ID: mdl-24828645
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebral Cortex / Calcium Signaling / Inositol 1,4,5-Trisphosphate Receptors / Alzheimer Disease / Neurons Type of study: Etiology_studies Limits: Animals Language: En Journal: J Neurosci Year: 2014 Document type: Article Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebral Cortex / Calcium Signaling / Inositol 1,4,5-Trisphosphate Receptors / Alzheimer Disease / Neurons Type of study: Etiology_studies Limits: Animals Language: En Journal: J Neurosci Year: 2014 Document type: Article Country of publication: Estados Unidos