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In vitro dosimetry of agglomerates.
Hirsch, V; Kinnear, C; Rodriguez-Lorenzo, L; Monnier, C A; Rothen-Rutishauser, B; Balog, S; Petri-Fink, A.
Affiliation
  • Hirsch V; Adolphe Merkle Institute, University of Fribourg, Route de l'Ancienne Papeterie, P.O. Box 209, Marly 1723, Switzerland.
Nanoscale ; 6(13): 7325-31, 2014 Jul 07.
Article in En | MEDLINE | ID: mdl-24853436
Agglomeration of nanoparticles in biological fluids is a pervasive phenomenon that leads to difficulty in the interpretation of results from in vitro exposure, primarily due to differing particokinetics of agglomerates to nanoparticles. Therefore, well-defined small agglomerates were designed that possessed different particokinetic profiles, and their cellular uptake was compared to a computational model of dosimetry. The approach used here paves the way for a better understanding of the impact of agglomeration on the nanoparticle-cell interaction.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Metal Nanoparticles Limits: Humans Language: En Journal: Nanoscale Year: 2014 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Metal Nanoparticles Limits: Humans Language: En Journal: Nanoscale Year: 2014 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido