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Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication.
Skerlj, Renato; Bridger, Gary; Zhou, Yuanxi; Bourque, Elyse; McEachern, Ernest; Danthi, Sanjay; Langille, Jonathan; Harwig, Curtis; Veale, Duane; Carpenter, Bryon; Ba, Tuya; Bey, Michael; Baird, Ian; Wilson, Trevor; Metz, Markus; MacFarland, Ron; Mosi, Renee; Bodart, Veronique; Wong, Rebecca; Fricker, Simon; Huskens, Dana; Schols, Dominique.
Affiliation
  • Skerlj R; Genzyme Corporation , 153 Second Avenue, Waltham, Massachusetts 02451, United States.
  • Bridger G; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Zhou Y; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Bourque E; Genzyme Corporation , 153 Second Avenue, Waltham, Massachusetts 02451, United States.
  • McEachern E; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Danthi S; Genzyme Corporation , 153 Second Avenue, Waltham, Massachusetts 02451, United States.
  • Langille J; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Harwig C; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Veale D; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Carpenter B; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Ba T; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Bey M; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Baird I; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Wilson T; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Metz M; Genzyme Corporation , 153 Second Avenue, Waltham, Massachusetts 02451, United States.
  • MacFarland R; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Mosi R; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Bodart V; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Wong R; Anormed Inc. , 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5 Canada.
  • Fricker S; Genzyme Corporation , 153 Second Avenue, Waltham, Massachusetts 02451, United States.
  • Huskens D; Rega Institute for Medical Research, Katholieke Universitett Leuven , Minderbroedersstraat 10, B-3000, Belgium.
  • Schols D; Rega Institute for Medical Research, Katholieke Universitett Leuven , Minderbroedersstraat 10, B-3000, Belgium.
ACS Med Chem Lett ; 3(3): 216-21, 2012 Mar 08.
Article in En | MEDLINE | ID: mdl-24900457
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: ACS Med Chem Lett Year: 2012 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: ACS Med Chem Lett Year: 2012 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos