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Discovery of AZD8931, an Equipotent, Reversible Inhibitor of Signaling by EGFR, HER2, and HER3 Receptors.
Barlaam, Bernard; Anderton, Judith; Ballard, Peter; Bradbury, Robert H; Hennequin, Laurent F A; Hickinson, D Mark; Kettle, Jason G; Kirk, George; Klinowska, Teresa; Lambert-van der Brempt, Christine; Trigwell, Cath; Vincent, John; Ogilvie, Donald.
Affiliation
  • Barlaam B; Centre de Recherches, AstraZeneca , Z.I. La Pompelle, B.P. 1050, Chemin de Vrilly, 51689 Reims, Cedex 2, France.
  • Anderton J; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
  • Ballard P; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
  • Bradbury RH; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
  • Hennequin LF; Centre de Recherches, AstraZeneca , Z.I. La Pompelle, B.P. 1050, Chemin de Vrilly, 51689 Reims, Cedex 2, France.
  • Hickinson DM; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
  • Kettle JG; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
  • Kirk G; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
  • Klinowska T; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
  • Lambert-van der Brempt C; Centre de Recherches, AstraZeneca , Z.I. La Pompelle, B.P. 1050, Chemin de Vrilly, 51689 Reims, Cedex 2, France.
  • Trigwell C; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
  • Vincent J; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
  • Ogilvie D; Oncology iMed, AstraZeneca , Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom.
ACS Med Chem Lett ; 4(8): 742-6, 2013 Aug 08.
Article in En | MEDLINE | ID: mdl-24900741
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2013 Document type: Article Affiliation country: Francia Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2013 Document type: Article Affiliation country: Francia Country of publication: Estados Unidos