Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not with insulin resistance.
Mol Cell Biol
; 34(17): 3305-20, 2014 Sep.
Article
in En
| MEDLINE
| ID: mdl-24958099
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
NF-E2-Related Factor 2
/
Non-alcoholic Fatty Liver Disease
/
Liver Cirrhosis, Experimental
Type of study:
Risk_factors_studies
Limits:
Animals
Language:
En
Journal:
Mol Cell Biol
Year:
2014
Document type:
Article
Affiliation country:
Reino Unido
Country of publication:
Estados Unidos