Current and future systemic treatment options in metastatic pancreatic cancer.
J Gastrointest Oncol
; 5(4): 280-95, 2014 Aug.
Article
in En
| MEDLINE
| ID: mdl-25083302
ABSTRACT
Although pancreatic adenocarcinoma is the fourth leading cause of cancer death, only modest improvement has been observed in the past two decades, single agent gemcitabine has been the only standard treatment in patients with advanced disease. Recently newer agents such as nab-paclitaxel, nimotuzumab and regimens such as FOLFIRINOX have been shown to have promising activity being superior to gemcitabine as a single agent. With better understanding of tumour biology coupled with the improvements in targeted and immunotherapies, there is increasing expectation for better response rates and extended survival in pancreatic cancer.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Gastrointest Oncol
Year:
2014
Document type:
Article
Affiliation country:
Turquía