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Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.
De Simone, V; Franzè, E; Ronchetti, G; Colantoni, A; Fantini, M C; Di Fusco, D; Sica, G S; Sileri, P; MacDonald, T T; Pallone, F; Monteleone, G; Stolfi, C.
Affiliation
  • De Simone V; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
  • Franzè E; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
  • Ronchetti G; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
  • Colantoni A; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
  • Fantini MC; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
  • Di Fusco D; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
  • Sica GS; Department of Surgery, University of Rome 'Tor Vergata', Rome, Italy.
  • Sileri P; Department of Surgery, University of Rome 'Tor Vergata', Rome, Italy.
  • MacDonald TT; Centre for Immunology and Infectious Disease, Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK.
  • Pallone F; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
  • Monteleone G; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
  • Stolfi C; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Oncogene ; 34(27): 3493-503, 2015 Jul.
Article in En | MEDLINE | ID: mdl-25174402

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / NF-kappa B / Interleukins / Interleukin-6 / Tumor Necrosis Factor-alpha / Interleukin-17 / STAT3 Transcription Factor Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2015 Document type: Article Affiliation country: Italia Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / NF-kappa B / Interleukins / Interleukin-6 / Tumor Necrosis Factor-alpha / Interleukin-17 / STAT3 Transcription Factor Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2015 Document type: Article Affiliation country: Italia Country of publication: Reino Unido