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Pak1 is required to maintain ventricular Ca²âº homeostasis and electrophysiological stability through SERCA2a regulation in mice.
Wang, Yanwen; Tsui, Hoyee; Ke, Yunbo; Shi, Ying; Li, Yatong; Davies, Laura; Cartwright, Elizabeth J; Venetucci, Luigi; Zhang, Henggui; Terrar, Derek A; Huang, Christopher L-H; Solaro, R John; Wang, Xin; Lei, Ming.
Affiliation
  • Wang Y; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Tsui H; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Ke Y; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Shi Y; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Li Y; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Davies L; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Cartwright EJ; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Venetucci L; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Zhang H; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Terrar DA; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Huang CL; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Solaro RJ; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Wang X; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
  • Lei M; From the Department of Pharmacology, University of Oxford, Oxford, United Kingdom (Y.W., D.A.T., M.L.); Institute of Cardiovascular Sciences, Faculty of Medicine and Human Sciences (Y.W., H.T., Y.L., L.D., E.J.C., L.V., M.L.), Faculty of Life Science (X.W.), School of Physics and Astronomy (H.Z.), U
Circ Arrhythm Electrophysiol ; 7(5): 938-48, 2014 Oct.
Article in En | MEDLINE | ID: mdl-25217043
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium / Tachycardia, Ventricular / Myocytes, Cardiac / Sarcoplasmic Reticulum Calcium-Transporting ATPases / P21-Activated Kinases / Heart Ventricles Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Circ Arrhythm Electrophysiol Journal subject: ANGIOLOGIA / CARDIOLOGIA Year: 2014 Document type: Article Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium / Tachycardia, Ventricular / Myocytes, Cardiac / Sarcoplasmic Reticulum Calcium-Transporting ATPases / P21-Activated Kinases / Heart Ventricles Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Circ Arrhythm Electrophysiol Journal subject: ANGIOLOGIA / CARDIOLOGIA Year: 2014 Document type: Article Country of publication: Estados Unidos