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Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies.
Bouvin-Pley, M; Morgand, M; Meyer, L; Goujard, C; Moreau, A; Mouquet, H; Nussenzweig, M; Pace, C; Ho, D; Bjorkman, P J; Baty, D; Chames, P; Pancera, M; Kwong, P D; Poignard, P; Barin, F; Braibant, M.
Affiliation
  • Bouvin-Pley M; Université François Rabelais, Inserm U966, Tours, France.
  • Morgand M; Université François Rabelais, Inserm U966, Tours, France.
  • Meyer L; Université Paris Sud, CESP Inserm U1018, Paris, France AP-HP Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.
  • Goujard C; Université Paris Sud, CESP Inserm U1018, Paris, France AP-HP Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.
  • Moreau A; Université François Rabelais, Inserm U966, Tours, France.
  • Mouquet H; Laboratory of Humoral Response to Pathogens, Department of Immunology, Institut Pasteur, Paris, France.
  • Nussenzweig M; Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.
  • Pace C; Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York, USA.
  • Ho D; Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York, USA.
  • Bjorkman PJ; California Institute of Technology, Pasadena, California, USA.
  • Baty D; CRCM, Inserm U1068, Institut Paoli-Calmettes, CNRS UMR7258, Marseille, France.
  • Chames P; CRCM, Inserm U1068, Institut Paoli-Calmettes, CNRS UMR7258, Marseille, France.
  • Pancera M; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, USA.
  • Kwong PD; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, USA.
  • Poignard P; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, USA International AIDS Vaccine Initiative Neutralizing Antibody Center, La Jolla, California, USA.
  • Barin F; Université François Rabelais, Inserm U966, Tours, France Laboratoire de Bactériologie-Virologie and Centre National de Reference du VIH, CHU Bretonneau, Tours, France.
  • Braibant M; Université François Rabelais, Inserm U966, Tours, France braibant@med.univ-tours.fr.
J Virol ; 88(23): 13910-7, 2014 Dec.
Article in En | MEDLINE | ID: mdl-25231299
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Envelope Protein gp120 / HIV Infections / HIV-1 / Genetic Drift / Antibodies, Neutralizing / Antibodies, Monoclonal Limits: Animals / Humans / Male Language: En Journal: J Virol Year: 2014 Document type: Article Affiliation country: Francia Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Envelope Protein gp120 / HIV Infections / HIV-1 / Genetic Drift / Antibodies, Neutralizing / Antibodies, Monoclonal Limits: Animals / Humans / Male Language: En Journal: J Virol Year: 2014 Document type: Article Affiliation country: Francia Country of publication: Estados Unidos