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PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
Wu, Chia-Yen C; Carpenter, Eileen S; Takeuchi, Kenneth K; Halbrook, Christopher J; Peverley, Louise V; Bien, Harold; Hall, Jason C; DelGiorno, Kathleen E; Pal, Debjani; Song, Yan; Shi, Chanjuan; Lin, Richard Z; Crawford, Howard C.
Affiliation
  • Wu CY; Department of Physiology and Biophysics, Stony Brook University, Stony Brook, New York.
  • Carpenter ES; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, New York.
  • Takeuchi KK; Department of Cancer Biology, Mayo Clinic Florida, Jacksonville, Florida.
  • Halbrook CJ; Department of Cancer Biology, Mayo Clinic Florida, Jacksonville, Florida; Department of Chemistry, Stony Brook University, Stony Brook, New York.
  • Peverley LV; Department of Cancer Biology, Mayo Clinic Florida, Jacksonville, Florida.
  • Bien H; Division of Hematology/Oncology, Stony Brook University, Stony Brook, New York.
  • Hall JC; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, New York; Department of Cancer Biology, Mayo Clinic Florida, Jacksonville, Florida.
  • DelGiorno KE; Department of Cancer Biology, Mayo Clinic Florida, Jacksonville, Florida; Molecular Genetics and Microbiology Graduate Program, Stony Brook University, Stony Brook, New York.
  • Pal D; Molecular and Cellular Biology Graduate Program, Stony Brook University, Stony Brook, New York.
  • Song Y; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, New York.
  • Shi C; Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Lin RZ; Department of Physiology and Biophysics, Stony Brook University, Stony Brook, New York; Medical Service, Northport VA Medical Center, Northport, New York. Electronic address: richard.lin@stonybrook.edu.
  • Crawford HC; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, New York; Department of Cancer Biology, Mayo Clinic Florida, Jacksonville, Florida. Electronic address: crawford.howard@mayo.edu.
Gastroenterology ; 147(6): 1405-16.e7, 2014 Dec.
Article in En | MEDLINE | ID: mdl-25311989
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neuropeptides / Adenocarcinoma / Proto-Oncogene Proteins p21(ras) / Phosphatidylinositol 3-Kinases / Rac1 GTP-Binding Protein / Carcinoma, Pancreatic Ductal Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Gastroenterology Year: 2014 Document type: Article Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neuropeptides / Adenocarcinoma / Proto-Oncogene Proteins p21(ras) / Phosphatidylinositol 3-Kinases / Rac1 GTP-Binding Protein / Carcinoma, Pancreatic Ductal Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Gastroenterology Year: 2014 Document type: Article Country of publication: Estados Unidos