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Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity.
Soncini, Debora; Caffa, Irene; Zoppoli, Gabriele; Cea, Michele; Cagnetta, Antonia; Passalacqua, Mario; Mastracci, Luca; Boero, Silvia; Montecucco, Fabrizio; Sociali, Giovanna; Lasigliè, Denise; Damonte, Patrizia; Grozio, Alessia; Mannino, Elena; Poggi, Alessandro; D'Agostino, Vito G; Monacelli, Fiammetta; Provenzani, Alessandro; Odetti, Patrizio; Ballestrero, Alberto; Bruzzone, Santina; Nencioni, Alessio.
Affiliation
  • Soncini D; From the Department of Internal Medicine.
  • Caffa I; From the Department of Internal Medicine.
  • Zoppoli G; the Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium, the Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
  • Cea M; From the Department of Internal Medicine, the Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139.
  • Cagnetta A; the Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139.
  • Passalacqua M; Department of Experimental Medicine, Section of Biochemistry, and Italian Institute of Biostructures and Biosystems, University of Genoa, 16132 Genoa, Italy.
  • Mastracci L; Department of Integrated Surgical and Diagnostic Sciences, Pathology Unit, University of Genoa, 16132 Genoa, Italy, the Istituto di Ricovero e Cura a Carattere Scientifico Azienda Ospedaliera Universitaria San Martino-Istituto Scientifico Tumori, Istituto Nazionale per la Ricerca sul Cancro, 16132 G
  • Boero S; the Istituto di Ricovero e Cura a Carattere Scientifico Azienda Ospedaliera Universitaria San Martino-Istituto Scientifico Tumori, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.
  • Montecucco F; From the Department of Internal Medicine, the Division of Cardiology, Foundation for Medical Researches, Department of Medical Specialties, University of Geneva, 1211 Geneva, Switzerland.
  • Sociali G; Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, and.
  • Lasigliè D; From the Department of Internal Medicine.
  • Damonte P; From the Department of Internal Medicine.
  • Grozio A; Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, and.
  • Mannino E; Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, and.
  • Poggi A; the Istituto di Ricovero e Cura a Carattere Scientifico Azienda Ospedaliera Universitaria San Martino-Istituto Scientifico Tumori, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.
  • D'Agostino VG; the Laboratory of Genomic Screening, Centre for Integrative Biology, University of Trento, 38123 Trento, Italy, and.
  • Monacelli F; From the Department of Internal Medicine.
  • Provenzani A; the Laboratory of Genomic Screening, Centre for Integrative Biology, University of Trento, 38123 Trento, Italy, and.
  • Odetti P; From the Department of Internal Medicine, the Istituto di Ricovero e Cura a Carattere Scientifico Azienda Ospedaliera Universitaria San Martino-Istituto Scientifico Tumori, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.
  • Ballestrero A; From the Department of Internal Medicine, the Istituto di Ricovero e Cura a Carattere Scientifico Azienda Ospedaliera Universitaria San Martino-Istituto Scientifico Tumori, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.
  • Bruzzone S; Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, and.
  • Nencioni A; From the Department of Internal Medicine, the Istituto di Ricovero e Cura a Carattere Scientifico Azienda Ospedaliera Universitaria San Martino-Istituto Scientifico Tumori, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy, alessio.nencioni@unige.it.
J Biol Chem ; 289(49): 34189-204, 2014 Dec 05.
Article in En | MEDLINE | ID: mdl-25331943

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Gene Expression Regulation, Neoplastic / Cytokines / Transforming Growth Factor beta1 / Nicotinamide Phosphoribosyltransferase / Epithelial-Mesenchymal Transition / Neoplasm Proteins Limits: Animals / Female / Humans Language: En Journal: J Biol Chem Year: 2014 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Gene Expression Regulation, Neoplastic / Cytokines / Transforming Growth Factor beta1 / Nicotinamide Phosphoribosyltransferase / Epithelial-Mesenchymal Transition / Neoplasm Proteins Limits: Animals / Female / Humans Language: En Journal: J Biol Chem Year: 2014 Document type: Article