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Variation in pre-PCR processing of FFPE samples leads to discrepancies in BRAF and EGFR mutation detection: a diagnostic RING trial.
Kapp, Joshua R; Diss, Tim; Spicer, James; Gandy, Michael; Schrijver, Iris; Jennings, Lawrence J; Li, Marilyn M; Tsongalis, Gregory J; de Castro, David Gonzalez; Bridge, Julia A; Wallace, Andrew; Deignan, Joshua L; Hing, Sandra; Butler, Rachel; Verghese, Eldo; Latham, Gary J; Hamoudi, Rifat A.
Affiliation
  • Kapp JR; Division of Surgery and Interventional Sciences, University College London, London, UK.
  • Diss T; University College London Advanced Diagnostics, University College London, London, UK.
  • Spicer J; Division of Research Oncology, Guy's and St. Thomas' Hospital NHS Trust, London, UK.
  • Gandy M; University College London Advanced Diagnostics, University College London, London, UK.
  • Schrijver I; Department of Pathology, Stanford University Medical Center, Stanford, USA.
  • Jennings LJ; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, USA.
  • Li MM; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, USA.
  • Tsongalis GJ; Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, USA.
  • de Castro DG; Institute of Cancer Research, The Royal Marsden Hospital NHS Trust, London, UK.
  • Bridge JA; Department of Pathology, University of Nebraska Medical Center, Omaha, USA.
  • Wallace A; Regional Genetics Laboratory, Central Manchester University Hospital NHS Trust, Manchester, UK.
  • Deignan JL; Department of Pathology and Laboratory Medicine, UCLA School of Medicine, Los Angeles, USA.
  • Hing S; Paediatric Malignancy Department, Great Ormond Street Hospital for Children NHS Trust, London, UK.
  • Butler R; All Wales Genetics Laboratory, Cardiff and Vale NHS Trust, Cardiff, UK.
  • Verghese E; Pathology and Tumour biology, University of Leeds, Leeds, UK.
  • Latham GJ; Asuragen, Austin, USA.
  • Hamoudi RA; Division of Surgery and Interventional Sciences, University College London, London, UK.
J Clin Pathol ; 68(2): 111-8, 2015 Feb.
Article in En | MEDLINE | ID: mdl-25430497

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Mutational Analysis / Polymerase Chain Reaction / Tissue Fixation / Paraffin Embedding / Proto-Oncogene Proteins B-raf / Laboratory Proficiency Testing / Fixatives / ErbB Receptors / Formaldehyde / Mutation Type of study: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Limits: Humans Country/Region as subject: America do norte / Europa Language: En Journal: J Clin Pathol Year: 2015 Document type: Article Affiliation country: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Mutational Analysis / Polymerase Chain Reaction / Tissue Fixation / Paraffin Embedding / Proto-Oncogene Proteins B-raf / Laboratory Proficiency Testing / Fixatives / ErbB Receptors / Formaldehyde / Mutation Type of study: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Limits: Humans Country/Region as subject: America do norte / Europa Language: En Journal: J Clin Pathol Year: 2015 Document type: Article Affiliation country: Reino Unido