A poroviscohyperelastic model for numerical analysis of mechanical behavior of single chondrocyte.
Comput Methods Biomech Biomed Engin
; 19(2): 126-36, 2016.
Article
in En
| MEDLINE
| ID: mdl-25588670
ABSTRACT
The aim of this paper is to use a poroviscohyperelastic (PVHE) model, which is developed based on the porohyperelastic (PHE) model to explore the mechanical deformation properties of single chondrocytes. Both creep and relaxation responses are investigated by using finite element analysis models of micropipette aspiration and atomic force microscopy experiments, respectively. The newly developed PVHE model is compared thoroughly with the standard neo-Hookean solid and PHE models. It has been found that the PVHE can accurately capture both creep and stress relaxation behaviors of chondrocytes better than other two models. Hence, the PVHE is a promising model to investigate mechanical properties of single chondrocytes.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chondrocytes
/
Elasticity
/
Models, Biological
Type of study:
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Comput Methods Biomech Biomed Engin
Journal subject:
ENGENHARIA BIOMEDICA
/
FISIOLOGIA
Year:
2016
Document type:
Article
Affiliation country:
Australia