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Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target.
Weingart, Melanie F; Roth, Jacquelyn J; Hutt-Cabezas, Marianne; Busse, Tracy M; Kaur, Harpreet; Price, Antoinette; Maynard, Rachael; Rubens, Jeffrey; Taylor, Isabella; Mao, Xing-Gang; Xu, Jingying; Kuwahara, Yasumichi; Allen, Sariah J; Erdreich-Epstein, Anat; Weissman, Bernard E; Orr, Brent A; Eberhart, Charles G; Biegel, Jaclyn A; Raabe, Eric H.
Affiliation
  • Weingart MF; Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Roth JJ; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Hutt-Cabezas M; Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Busse TM; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Kaur H; Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Price A; Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Maynard R; Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Rubens J; Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Taylor I; Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Mao XG; Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Xu J; Division of Hematology, Oncology, and Blood & Bone Marrow Transplant, Children's Hospital Los Angeles, Los Angeles, CA, USA.
  • Kuwahara Y; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
  • Allen SJ; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Erdreich-Epstein A; Division of Hematology, Oncology, and Blood & Bone Marrow Transplant, Children's Hospital Los Angeles, Los Angeles, CA, USA.
  • Weissman BE; The Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
  • Orr BA; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
  • Eberhart CG; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Biegel JA; Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Raabe EH; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Oncotarget ; 6(5): 3165-77, 2015 Feb 20.
Article in En | MEDLINE | ID: mdl-25638158

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Teratoma / Brain Neoplasms / RNA-Binding Proteins / Rhabdoid Tumor / MAP Kinase Signaling System / Protein Kinase Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Oncotarget Year: 2015 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Teratoma / Brain Neoplasms / RNA-Binding Proteins / Rhabdoid Tumor / MAP Kinase Signaling System / Protein Kinase Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Oncotarget Year: 2015 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos