Synthesis of orotidine by intramolecular nucleosidation.
Chem Commun (Camb)
; 51(26): 5618-21, 2015 Apr 04.
Article
in En
| MEDLINE
| ID: mdl-25714895
ABSTRACT
An intramolecular nucleosidation approach provides easy access to orotidine in high yields. Notably, orotate itself is used as a leaving group at the anomeric position. This method has the potential for facile access to derivatives of orotidine of therapeutic interest, with implications for prebiotic formation of nucleosides.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Uridine
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2015
Document type:
Article