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The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly.
Sidrauski, Carmela; McGeachy, Anna M; Ingolia, Nicholas T; Walter, Peter.
Affiliation
  • Sidrauski C; Department of Biochemistry and Biophysics, Howard Hughes Medical Institute, University of California, San Francis, San Francisco, United States.
  • McGeachy AM; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
  • Ingolia NT; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
  • Walter P; Department of Biochemistry and Biophysics, Howard Hughes Medical Institute, University of California, San Francis, San Francisco, United States.
Elife ; 42015 Feb 26.
Article in En | MEDLINE | ID: mdl-25719440
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Protein Biosynthesis / Eukaryotic Initiation Factor-2 / Cyclohexylamines / Cytoplasmic Granules / Acetamides Type of study: Prognostic_studies Limits: Animals Language: En Journal: Elife Year: 2015 Document type: Article Affiliation country: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Protein Biosynthesis / Eukaryotic Initiation Factor-2 / Cyclohexylamines / Cytoplasmic Granules / Acetamides Type of study: Prognostic_studies Limits: Animals Language: En Journal: Elife Year: 2015 Document type: Article Affiliation country: Estados Unidos