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Epigenetic clustering of gastric carcinomas based on DNA methylation profiles at the precancerous stage: its correlation with tumor aggressiveness and patient outcome.
Yamanoi, Kazuhiro; Arai, Eri; Tian, Ying; Takahashi, Yoriko; Miyata, Sayaka; Sasaki, Hiroki; Chiwaki, Fumiko; Ichikawa, Hitoshi; Sakamoto, Hiromi; Kushima, Ryoji; Katai, Hitoshi; Yoshida, Teruhiko; Sakamoto, Michiie; Kanai, Yae.
Affiliation
  • Yamanoi K; Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo 104-0045, Japan, Department of Pathology, Keio University School of Medicine, Tokyo 160-8582, Japan.
  • Arai E; Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo 104-0045, Japan, earai@ncc.go.jp.
  • Tian Y; Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
  • Takahashi Y; Bioscience Department, Business Development Division, Mitsui Knowledge Industry Co., Ltd., Tokyo 105-6215, Japan.
  • Miyata S; Bioscience Department, Business Development Division, Mitsui Knowledge Industry Co., Ltd., Tokyo 105-6215, Japan.
  • Sasaki H; Department of Translational Oncology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
  • Chiwaki F; Department of Translational Oncology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
  • Ichikawa H; Division of Genetics, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
  • Sakamoto H; Division of Genetics, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
  • Kushima R; Department of Pathology and Clinical Laboratories, Pathology Division, National Cancer Center Hospital, Tokyo 104-0045, Japan and.
  • Katai H; Department of Gastric Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan.
  • Yoshida T; Division of Genetics, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
  • Sakamoto M; Department of Pathology, Keio University School of Medicine, Tokyo 160-8582, Japan.
  • Kanai Y; Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
Carcinogenesis ; 36(5): 509-20, 2015 May.
Article in En | MEDLINE | ID: mdl-25740824
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precancerous Conditions / Stomach Neoplasms / Biomarkers, Tumor / Gene Expression Regulation, Neoplastic / DNA Methylation / Epigenesis, Genetic / Gastric Mucosa / Neoplasm Recurrence, Local Type of study: Observational_studies / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Carcinogenesis Year: 2015 Document type: Article Affiliation country: Japón
Fulltext
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Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precancerous Conditions / Stomach Neoplasms / Biomarkers, Tumor / Gene Expression Regulation, Neoplastic / DNA Methylation / Epigenesis, Genetic / Gastric Mucosa / Neoplasm Recurrence, Local Type of study: Observational_studies / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Carcinogenesis Year: 2015 Document type: Article Affiliation country: Japón