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Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease.
Harrington, Charles R; Storey, John M D; Clunas, Scott; Harrington, Kathleen A; Horsley, David; Ishaq, Ahtsham; Kemp, Steven J; Larch, Christopher P; Marshall, Colin; Nicoll, Sarah L; Rickard, Janet E; Simpson, Michael; Sinclair, James P; Storey, Lynda J; Wischik, Claude M.
Affiliation
  • Harrington CR; From the School of Medicine and Dentistry, University of Aberdeen, Aberdeen AB25 2ZP, United Kingdom, TauRx Therapeutics Ltd., Singapore 068805, and the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom c.harrington@abdn.ac.uk.
  • Storey JM; TauRx Therapeutics Ltd., Singapore 068805, and the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Clunas S; the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Harrington KA; From the School of Medicine and Dentistry, University of Aberdeen, Aberdeen AB25 2ZP, United Kingdom.
  • Horsley D; From the School of Medicine and Dentistry, University of Aberdeen, Aberdeen AB25 2ZP, United Kingdom.
  • Ishaq A; the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Kemp SJ; the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Larch CP; the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Marshall C; the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Nicoll SL; the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Rickard JE; From the School of Medicine and Dentistry, University of Aberdeen, Aberdeen AB25 2ZP, United Kingdom.
  • Simpson M; the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Sinclair JP; the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Storey LJ; the Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom.
  • Wischik CM; From the School of Medicine and Dentistry, University of Aberdeen, Aberdeen AB25 2ZP, United Kingdom, TauRx Therapeutics Ltd., Singapore 068805, and cmw@taurx.com.
J Biol Chem ; 290(17): 10862-75, 2015 Apr 24.
Article in En | MEDLINE | ID: mdl-25759392

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Alzheimer Disease / Protein Aggregation, Pathological Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Alzheimer Disease / Protein Aggregation, Pathological Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos