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SCD5-induced oleic acid production reduces melanoma malignancy by intracellular retention of SPARC and cathepsin B.
Bellenghi, Maria; Puglisi, Rossella; Pedini, Francesca; De Feo, Alessandra; Felicetti, Federica; Bottero, Lisabianca; Sangaletti, Sabina; Errico, Maria Cristina; Petrini, Marina; Gesumundo, Cinzia; Denaro, Massimo; Felli, Nadia; Pasquini, Luca; Tripodo, Claudio; Colombo, Mario Paolo; Carè, Alessandra; Mattia, Gianfranco.
Affiliation
  • Bellenghi M; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Puglisi R; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Pedini F; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • De Feo A; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Felicetti F; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Bottero L; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Sangaletti S; Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Errico MC; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Petrini M; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Gesumundo C; Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy.
  • Denaro M; Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy.
  • Felli N; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Pasquini L; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Tripodo C; Department of Health Sciences, University of Palermo, Italy.
  • Colombo MP; Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Carè A; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Mattia G; Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
J Pathol ; 236(3): 315-25, 2015 Jul.
Article in En | MEDLINE | ID: mdl-25802234
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stearoyl-CoA Desaturase / Cathepsin B / Gene Expression Regulation, Neoplastic / Osteonectin / Oleic Acid / Melanoma Limits: Humans Language: En Journal: J Pathol Year: 2015 Document type: Article Affiliation country: Italia Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stearoyl-CoA Desaturase / Cathepsin B / Gene Expression Regulation, Neoplastic / Osteonectin / Oleic Acid / Melanoma Limits: Humans Language: En Journal: J Pathol Year: 2015 Document type: Article Affiliation country: Italia Country of publication: Reino Unido