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Evaluation of the effect of food and gastric pH on the single-dose pharmacokinetics of cabozantinib in healthy adult subjects.
Nguyen, Linh; Holland, Jaymes; Mamelok, Richard; Laberge, Marie-Kristine; Grenier, Julie; Swearingen, Dennis; Armas, Danielle; Lacy, Steven.
Affiliation
  • Nguyen L; Exelixis, Inc., San Francisco, CA, USA.
  • Holland J; Exelixis, Inc., San Francisco, CA, USA.
  • Mamelok R; Mamelok Consulting, Palo Alto, CA, USA.
  • Laberge MK; Celerion, Montreal, QC, Canada.
  • Grenier J; Celerion, Montreal, QC, Canada.
  • Swearingen D; Celerion, Tempe, AZ, USA.
  • Armas D; Celerion, Tempe, AZ, USA.
  • Lacy S; Exelixis, Inc., San Francisco, CA, USA.
J Clin Pharmacol ; 55(11): 1293-302, 2015 Nov.
Article in En | MEDLINE | ID: mdl-25907407
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Protein Kinase Inhibitors / Proton Pump Inhibitors / Esomeprazole / Anilides Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: J Clin Pharmacol Year: 2015 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Protein Kinase Inhibitors / Proton Pump Inhibitors / Esomeprazole / Anilides Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: J Clin Pharmacol Year: 2015 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido