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Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammation.
Ullah, Md Ashik; Revez, Joana A; Loh, Zhixuan; Simpson, Jennifer; Zhang, Vivian; Bain, Lisa; Varelias, Antiopi; Rose-John, Stefan; Blumenthal, Antje; Smyth, Mark J; Hill, Geoffrey R; Sukkar, Maria B; Ferreira, Manuel A R; Phipps, Simon.
Affiliation
  • Ullah MA; Woolcock Institute of Medical Research, Sydney Medical School, University of Sydney, Sydney, Australia; Laboratory for Respiratory Neuroscience and Mucosal Immunity, School of Biomedical Sciences, University of Queensland, Brisbane, Australia; QIMR Berghofer Medical Research Institute, Brisbane, Aus
  • Revez JA; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Loh Z; Laboratory for Respiratory Neuroscience and Mucosal Immunity, School of Biomedical Sciences, University of Queensland, Brisbane, Australia.
  • Simpson J; Laboratory for Respiratory Neuroscience and Mucosal Immunity, School of Biomedical Sciences, University of Queensland, Brisbane, Australia.
  • Zhang V; Laboratory for Respiratory Neuroscience and Mucosal Immunity, School of Biomedical Sciences, University of Queensland, Brisbane, Australia.
  • Bain L; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Varelias A; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Rose-John S; Department of Biochemistry, Christian-Albrechts-Universität of Kiel, Kiel, Germany.
  • Blumenthal A; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia.
  • Smyth MJ; QIMR Berghofer Medical Research Institute, Brisbane, Australia; School of Medicine, University of Queensland, Herston, Australia.
  • Hill GR; QIMR Berghofer Medical Research Institute, Brisbane, Australia; Department of Bone Marrow Transplantation, Royal Brisbane Hospital, Brisbane, Australia.
  • Sukkar MB; Woolcock Institute of Medical Research, Sydney Medical School, University of Sydney, Sydney, Australia; School of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia.
  • Ferreira MA; QIMR Berghofer Medical Research Institute, Brisbane, Australia. Electronic address: manuel.ferreira@qimrberghofer.edu.au.
  • Phipps S; Laboratory for Respiratory Neuroscience and Mucosal Immunity, School of Biomedical Sciences, University of Queensland, Brisbane, Australia. Electronic address: s.phipps@uq.edu.au.
J Allergy Clin Immunol ; 136(4): 1065-73, 2015 Oct.
Article in En | MEDLINE | ID: mdl-25930193
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Signal Transduction / Interleukin-6 / Receptors, Antigen, T-Cell, gamma-delta / Th2 Cells / Receptors, Interleukin-6 / Th17 Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Allergy Clin Immunol Year: 2015 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Signal Transduction / Interleukin-6 / Receptors, Antigen, T-Cell, gamma-delta / Th2 Cells / Receptors, Interleukin-6 / Th17 Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Allergy Clin Immunol Year: 2015 Document type: Article