Randomized, double-blinded, vehicle-controlled, split-face study to evaluate the effects of topical application of a Gold Silk Sericin/Niacinamide/Signaline complex on biophysical parameters related to skin ageing.
Int J Cosmet Sci
; 37(6): 606-12, 2015 Dec.
Article
in En
| MEDLINE
| ID: mdl-25940759
ABSTRACT
OBJECTIVE:
To investigate the effects of topical application of a Gold Silk Sericin (GSS) complex on biophysical parameters related to skin ageing.METHODS:
A range of non-invasive bioengineering methods were deployed in an 8-week randomized, double-blinded, vehicle-controlled, split-face study among 40 female subjects aged 40-70. Endpoints measured included expert grades of skin condition, stratum corneum (SC) hydration, SC barrier function, elasticity and surface topography.RESULTS:
The GSS complex produced significant single-variable (P < 0.05) improvements in SC hydration, barrier function, elasticity and surface topography compared with the Vehicle control.CONCLUSION:
The GSS complex examined in this study represents an interesting new cosmetic topical technology with which to address multiple aspects of aged/photoaged female facial skin.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin Aging
/
Niacinamide
/
Sericins
Type of study:
Clinical_trials
Limits:
Humans
Language:
En
Journal:
Int J Cosmet Sci
Year:
2015
Document type:
Article
Affiliation country:
Italia