Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort.

Chi, Kwan-Hwa; Ko, Hui-Ling; Yang, Kai-Lin; Lee, Cheng-Yen; Chi, Mau-Shin; Kao, Shang-Jyh

Chi, Kwan-Hwa; Ko, Hui-Ling; Yang, Kai-Lin; Lee, Cheng-Yen; Chi, Mau-Shin; Kao, Shang-Jyh.

Affiliation

Chi KH; Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Ko HL; School of Medicine and Institute of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan.
Yang KL; Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Lee CY; Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Chi MS; Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Kao SJ; Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.

Oncotarget ; 6(18): 16735-45, 2015 Jun 30.

Article in En | MEDLINE | ID: mdl-25944689

Subject(s)
Key words

autophagy; hydroxychloroquine; metronomic chemotherapy; rapamycin

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Antineoplastic Combined Chemotherapy Protocols / Sirolimus / Hydroxychloroquine / Neoplasms Type of study: Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Oncotarget Year: 2015 Document type: Article Affiliation country: Taiwán Country of publication: Estados Unidos

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google