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Early specialist care for diabetes: who benefits most? A propensity score-matched cohort study.
Booth, G L; Shah, B R; Austin, P C; Hux, J E; Luo, J; Lok, C E.
Affiliation
  • Booth GL; Department of Medicine, University of Toronto, Toronto, ON, Canada.
  • Shah BR; Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON, Canada.
  • Austin PC; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.
  • Hux JE; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.
  • Luo J; Department of Medicine, University of Toronto, Toronto, ON, Canada.
  • Lok CE; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.
Diabet Med ; 33(1): 111-8, 2016 Jan.
Article in En | MEDLINE | ID: mdl-25981183
ABSTRACT

AIMS:

To examine whether early endocrinologist care reduces the risk of cardiovascular complications among newly diagnosed patients with diabetes of differing complexity.

METHODS:

We conducted a population-based propensity score-matched cohort study using provincial health data from Ontario, Canada. Adults (≥ 30 years) diagnosed with diabetes between 1 April 1998 and 31 March 2006 who received endocrinologist care in the first year of diagnosis were matched to a comparison group receiving primary care alone (N = 79 020) based on propensity scores and medical complexity (assigned using information on chronic conditions). Individuals were followed for 3- and 5-year outcomes, including non-fatal acute myocardial infarction or coronary heart disease death (primary endpoint), major cardiovascular events (acute myocardial infarction, stroke) or all-cause death, amputation and end-stage renal disease.

RESULTS:

Among medically complex patients, early endocrinologist care was associated with a lower 3-year incidence of the primary endpoint (hazard ratio 0.89, 95% CI 0.78-1.01) and major cardiovascular events or all-cause death (hazard ratio 0.91, 95% CI 0.85-0.97). These effects persisted after accounting for a higher incidence of end-stage renal disease on follow-up and were greatest in those with ≥ 3 visits to an endocrinologist (primary endpoint hazard ratio 0.69, 95% CI 0.56-0.86 and 0.61, 95% CI 0.45-0.82, for unadjusted and end-stage renal disease adjusted analyses, respectively). In contrast, no benefit was observed in the non-medically complex subgroup. Overall effects were similar at 5 years.

CONCLUSIONS:

Early endocrinologist care is associated with a lower incidence of cardiovascular events and death among newly diagnosed patients with diabetes who have comorbid medical conditions.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Specialization / Cardiovascular Diseases / Evidence-Based Medicine / Diabetes Mellitus, Type 2 / Diabetic Angiopathies / Endocrinology / Diabetic Cardiomyopathies Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Country/Region as subject: America do norte Language: En Journal: Diabet Med Journal subject: ENDOCRINOLOGIA Year: 2016 Document type: Article Affiliation country: Canadá

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Specialization / Cardiovascular Diseases / Evidence-Based Medicine / Diabetes Mellitus, Type 2 / Diabetic Angiopathies / Endocrinology / Diabetic Cardiomyopathies Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Country/Region as subject: America do norte Language: En Journal: Diabet Med Journal subject: ENDOCRINOLOGIA Year: 2016 Document type: Article Affiliation country: Canadá
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