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Identification of a Compound That Disrupts Binding of Amyloid-ß to the Prion Protein Using a Novel Fluorescence-based Assay.
Risse, Emmanuel; Nicoll, Andrew J; Taylor, William A; Wright, Daniel; Badoni, Mayank; Yang, Xiaofan; Farrow, Mark A; Collinge, John.
Affiliation
  • Risse E; From the Medical Research Council (MRC) Prion Unit and Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom.
  • Nicoll AJ; From the Medical Research Council (MRC) Prion Unit and Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom.
  • Taylor WA; From the Medical Research Council (MRC) Prion Unit and Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom.
  • Wright D; From the Medical Research Council (MRC) Prion Unit and Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom.
  • Badoni M; From the Medical Research Council (MRC) Prion Unit and Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom.
  • Yang X; From the Medical Research Council (MRC) Prion Unit and Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom.
  • Farrow MA; From the Medical Research Council (MRC) Prion Unit and Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom m.farrow@prion.ucl.ac.uk.
  • Collinge J; From the Medical Research Council (MRC) Prion Unit and Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom j.collinge@prion.ucl.ac.uk.
J Biol Chem ; 290(27): 17020-8, 2015 Jul 03.
Article in En | MEDLINE | ID: mdl-25995455
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Binding / Trypan Blue / Amyloid beta-Peptides / PrPC Proteins Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Binding / Trypan Blue / Amyloid beta-Peptides / PrPC Proteins Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos