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RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients.
Golan, Talia; Khvalevsky, Elina Zorde; Hubert, Ayala; Gabai, Rachel Malka; Hen, Naama; Segal, Amiel; Domb, Abraham; Harari, Gil; David, Eliel Ben; Raskin, Stephen; Goldes, Yuri; Goldin, Eran; Eliakim, Rami; Lahav, Maor; Kopleman, Yael; Dancour, Alain; Shemi, Amotz; Galun, Eithan.
Affiliation
  • Golan T; The Sackler School of Medicine, The Chaim Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel.
  • Khvalevsky EZ; Silenseed Ltd., Jerusalem, Israel.
  • Hubert A; Sharett Institute of Oncology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
  • Gabai RM; Silenseed Ltd., Jerusalem, Israel.
  • Hen N; Silenseed Ltd., Jerusalem, Israel.
  • Segal A; The Gastroenterology Institute, Shaare Zedek Medical Centre, Jerusalem, Israel.
  • Domb A; Institute of Drug Research, School of Pharmacy-Faculty of Medicine, Center for Nanoscience and Nanotechnology and The Alex Grass Centre for Drug Design and Synthesis, The Hebrew University of Jerusalem, Jerusalem, Israel.
  • Harari G; MediStat Ltd., Jerusalem, Israel.
  • David EB; Hadassah-Hebrew University Medical Centre, Jerusalem, Israel.
  • Raskin S; The Sackler School of Medicine, The Chaim Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel.
  • Goldes Y; The Sackler School of Medicine, The Chaim Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel.
  • Goldin E; The Gastroenterology Institute, Shaare Zedek Medical Center, Jerusalem, Israel.
  • Eliakim R; The Sackler School of Medicine, The Chaim Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel.
  • Lahav M; The Sackler School of Medicine, The Chaim Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel.
  • Kopleman Y; Gastroenterology Institute, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
  • Dancour A; The Gastroenterology Institute, Shaare Zedek Medical Center, Jerusalem, Israel.
  • Shemi A; Silenseed Ltd., Jerusalem, Israel.
  • Galun E; The Goldyne Savad Institute for Gene Therapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Oncotarget ; 6(27): 24560-70, 2015 Sep 15.
Article in En | MEDLINE | ID: mdl-26009994
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Proto-Oncogene Proteins p21(ras) / Carcinoma, Pancreatic Ductal / RNA, Small Interfering / Drug Implants / Molecular Targeted Therapy / RNAi Therapeutics Type of study: Clinical_trials Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Oncotarget Year: 2015 Document type: Article Affiliation country: Israel Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Proto-Oncogene Proteins p21(ras) / Carcinoma, Pancreatic Ductal / RNA, Small Interfering / Drug Implants / Molecular Targeted Therapy / RNAi Therapeutics Type of study: Clinical_trials Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Oncotarget Year: 2015 Document type: Article Affiliation country: Israel Country of publication: Estados Unidos